Acoustical
Neuro-Modulation as a Treatment for Anxiety
The Hartwell Foundation has
recently committed to support a rigorous pilot study at
Cornell Weill College of Medicine on the effectiveness
of sound as a means to reduce anxiety in children. An
algorithm that takes into account amplitude, frequency
and phase modulation associated with the well-known EEG
frequency bands of α, β1, β2, θ, δ and ϒ generates the
acoustic signal. Referred to as Acoustical
Neuro-Modulation (ANM), the inventors hypothesize that
the brain response to such modulated sound influences
the neural transduction of the
hypothalamic-pituitary-adrenocortical system, thereby
modulating the release of neurotransmitters to influence
psychological and physiological behavior. If the
clinical trial is successful in demonstrating a
reduction in anxiety following administration of ANM,
the Foundation will seek to explore the effectiveness of
the approach on anxiety associated with Autism Spectrum
Disorder.
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